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英国迷信家研收回3D打印眼角膜 无望有限量供给

工夫:2018-06-09 20:25 阅读:

Human corneas have successfully been 3D printed for the first time by scientists at Newcastle University in England. 英国纽卡斯尔大学的迷信家初次乐成接纳3D技能打印出人类眼角膜。 By mixing stem cells from a healthy donor cornea with alginate, a gel derived from seaweed, and collagen, researchers managed to create a "bio-ink" solution that can be printed. 迷信家经过未来自安康供体角膜的干细胞与藻盐酸(来自海藻的凝胶)和胶原卵白混淆在一同,发明出可以打印的“生物墨水”溶液。 This bio-ink then would be successfully expelled out of the printer in concentric circles in the shape of a cornea in less than 10 minutes, according to a paper published in Experimental Eye Research. 之后,3D打印机可以把这种生物墨水乐成打印成眼角膜的同心圆状,整个进程仅需10分钟。这项研讨效果宣布在《实行性眼科研讨》期刊上。 "Our unique bio-gel -- a combination of alginate and collagen -- keeps the stem cells alive while producing a material which is stiff enough to hold its shape but soft enough to be squeezed out the nozzle of a 3D printer," said lead researcher Che Connon in a press release. 首席研讨员彻-康农在旧事稿中说:“我们无独有偶的生物墨水由藻盐酸和胶原卵白制成,使干细胞坚持生机,同时制造出充足坚固的资料以坚持其外形,并且充足柔软以从3D打印机的喷嘴挤出。”

Connon's team also showed it is possible to create a cornea that matches a patient's unique specifications. 康农的团队还向人们展现出,打印出契合患者差别特点的角膜是完全可行的。 By taking the dimensions of the patient's actual cornea with scans, scientists can use the data to print a cornea that matches its size and shape. 迷信家经过扫描患者的眼睛来量取其真实角膜的尺寸,之后运用这些数据打印出与其巨细和外形相配的眼角膜。 The 3D printed corneas will now have to undergo further testing but it is hoped the technique could be in regular use within five years. 3D打印的人类角膜将需求停止进一步测试,但这一技能无望在5年内投入惯例运用。 Professor Connon said the research could help with the worldwide shortage of corneas for transplant. 康农传授说,这项研讨有助于缓解环球范畴内的眼角膜移植供体充足题目。 Currently around 10 million people worldwide each year require surgery to prevent corneal blindness, and another five million already suffer total blindness from corneal scarring caused by burns, lacerations, abrasion or disease. 现在环球每年有约莫1000万人需求移植角膜来避免角膜盲。另有500万人由于烧伤、扯破、擦伤或疾病招致角膜瘢痕而完全失明。